HGH CANCER – SIDE EFFECTS

Various news reporters and medical doctors on television have been warning the public about HGH side effects and in particularly about the increased risk of hgh cancer side effects. They cite various clinical trials and studies that indicate an increased risk of cancer which all sounds very convincing on the surface. Anyone who really investigates all the evidence will be amazed as to why all these news reporters and medical doctors seem to be the only ones that are ever on television and are so prolific on the Internet. The facts are that there are very large clinical trials that clearly show that HGH therapy significantly reduced the risk of cancer.

All the clinical trials that I have read which point towards an increased risk of cancer are skewed in one way or another to favor increased risk of hgh cancer side effects. It should be pointed out that testing in animals where very large doses of growth hormone are used clearly shows a very significant increased risk of cancer. If one uses injectable HGH and overdoses in large amounts there is no doubt that there's a very significant increased risk of cancer. What is misleading is to cite so-called evidence of increased risk of cancer in those using HGH therapy in the normal small doses which results in such significant and multifaceted health benefits. In earlier testing with HGH researchers did have some serious concerns about the increased risk of cancer.

When HGH was used in culture it stimulated the growth of leukemia cancer cells and also very large doses of growth hormone induced cancer in laboratory animals and also promoted tumors in rats. According to Pharmacia Upjohn in 1998, there has not been clear specific tests done for cancer-causing potential with HGH and tests on chromosomes in living animals and in cells in culture have not shown any evidence of mutation which is the first step in the development of cancer. The point that HGH put into cells and culture produced cancer is misleading and far from any evidence that can be cited for increased risk of cancer compared to actual human trials.

So what kind of trials were used in humans to point towards an increased risk of hgh cancer side effects? There are medical doctors like Samuel S. Epstein, professor of environmental medicine at the University of Illinois school of public health. He is very critical of using any type of HGH and supposedly cites evidence from prestigious peer-reviewed scientific journals that he claims show that an increased levels of IGF-1 are significantly related to strong increased risks of colon, prostate and breast cancers. It's too bad that he does not actually show these so that we can see if they really apply or even exist. I have yet to see any evidence that is not misleading in one way or another, that he can show or anyone else, that increased levels of IGF-1 significantly increases the risk of hgh cancer side effects.

After many hundreds of clinical studies on HGH therapy some of the world's leading and endocrinologists and scientific researchers came together in October 1999 at the Johns Hopkins School of Medicine for a Growth Hormone/Growth Factors Symposium. One of the most significant conclusions at this event was that "GH replacement therapy in adults ... is not associated with any increase in mortality." If Dr. Samuel S. Epstein has such great conclusions why would they contradict such clear conclusions from those that are experts in this very specialized field of endocrinology.

In 2002 two studies came out which caused a lot of confusion and alarm among the public as to the safety of HGH therapy in relation to cancer. The first appeared in the July 27, 2002 issue of The Lancet. This was in the United Kingdom in which Dr. Swerdlow and his colleagues tracked 1848 people who have received HGH as children. They concluded that collectively as a group there was a threefold increased risk of dying from cancer among these people. He also admitted that the study was incapable of showing a direct causative effect between HGH replacement and cancer. Doctor Swerdlow also stated that "there are risks about tenfold to colorectal cancer and Hodgkin's disease." The problem with this study is that they were using it on children because their bodies were not producing HGH and as a result were stunted and needed the growth hormone to grow. They were also using a particular kind of human pituitary growth hormone extracted from tissue that was not identical to the HGH the human body produces which is the kind used today known as synthetic (recombinant) HGH. This useage was discontinued in 1985 in England because it became clearly linked to mad cow disease in the US through the extraction process from the brains of animals.

One week after this report in the Lancet a study came out by Dr. David Cook and endocrinologist at Oregon health and Science University. This report appeared in the Journal of American College of Physicians American Society of Internal Medicine in the August 6, 2002 issue of Annals of Internal Medicine. In this report Dr. Cook explains that the kind of studies that are epidemiological - which would include the Swerdlow study in the Lancet mentioned above - suggest there is an increase in cancers in normal people that corresponds to their elevated levels of circulating free IGF-1. Dr. Cook points out that "high-normal IGF-1 concentrations may be a marker for cancer but are not causally related to inducement or growth of cancer." This is because HGH therapy can cause increased serum concentrations of IGF-1 coupled with reduced levels of binding proteins that take up IGF-1. Dr. Cooke's report also stated "appropriate growth hormone replacement therapy is associated with normalization, not elevation, of serum IGF-1 concentrations. In addition, levels of binding proteins are increased with growth hormone replacement, along with levels of IGF-1, resulting in normal, not elevated, free IGF-1 concentrations."

It is known fact that HGH therapy significantly strengthens the immune system. For example it regrows the thymus gland so that it can produce far more of the important material that increases the strength of the immune system. When the immune system is strong it can destroy cancer cells before they get a hold in the body. As I mentioned, there are large clinical trials of older people that clearly show that HGH therapy actually reduced the risk of cancer. For example, Dr. Edmund Chein treated 800 patients with HGH therapy between 1944 in 1996 who were all older than 40 years old. When you take into account the normal incidence cancer rate some of them should have gotten cancer and yet none did which is amazing. This clearly shows the protective effect of HGH therapy. What is even more astounding is that PSA levels which is a marker of prostate problems including cancer did not increase in any of the male patients.